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Celastrol Alleviates Autoimmune Hepatitis Through the PI3K/AKT Signaling Pathway Based on Network Pharmacology and Experiments
Objective: This work aims to explore the potential targets and underlying therapeutic mechanisms of celastrol in autoimmune hepatitis (AIH) through network pharmacology and experiments on Laboratory Animals. Methods: A drug-target interaction network was constructed to predict the possible targets o...
Autores principales: | Wang, Shuhui, Huang, Zheng, Lei, Yu, Han, Xu, Tian, Dean, Gong, Jin, Liu, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960436/ https://www.ncbi.nlm.nih.gov/pubmed/35359864 http://dx.doi.org/10.3389/fphar.2022.816350 |
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