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Impact of cyclic changes in pharmacokinetics and absorbed dose in pediatric neuroblastoma patients receiving [(177)Lu]Lu-DOTATATE

PURPOSE: Recent reports personalizing the administered activity (AA) of each cycle of peptide receptor radionuclide therapy based on the predicted absorbed dose (AD) to the kidneys (dose-limiting organ) have been promising. Assuming identical renal pharmacokinetics for each cycle is pragmatic, howev...

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Detalles Bibliográficos
Autores principales: Malcolm, Javian C., Falzone, Nadia, Gains, Jennifer E., Aldridge, Matthew D., Mirando, David, Lee, Boon Q., Gaze, Mark N., Vallis, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960523/
https://www.ncbi.nlm.nih.gov/pubmed/35347483
http://dx.doi.org/10.1186/s40658-022-00436-4