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PCSK9 acts as a key regulator of Aβ clearance across the blood–brain barrier

Despite the neurodegenerative disorder Alzheimer’s disease (AD) is the most common form of dementia in late adult life, there is currently no therapy available to prevent the onset or slow down the progression of AD. The progressive cognitive decline in AD correlates with a successive accumulation o...

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Detalles Bibliográficos
Autores principales: Mazura, Alexander D., Ohler, Anke, Storck, Steffen E., Kurtyka, Magdalena, Scharfenberg, Franka, Weggen, Sascha, Becker-Pauly, Christoph, Pietrzik, Claus U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960591/
https://www.ncbi.nlm.nih.gov/pubmed/35344086
http://dx.doi.org/10.1007/s00018-022-04237-x