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PCSK9 acts as a key regulator of Aβ clearance across the blood–brain barrier
Despite the neurodegenerative disorder Alzheimer’s disease (AD) is the most common form of dementia in late adult life, there is currently no therapy available to prevent the onset or slow down the progression of AD. The progressive cognitive decline in AD correlates with a successive accumulation o...
Autores principales: | Mazura, Alexander D., Ohler, Anke, Storck, Steffen E., Kurtyka, Magdalena, Scharfenberg, Franka, Weggen, Sascha, Becker-Pauly, Christoph, Pietrzik, Claus U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960591/ https://www.ncbi.nlm.nih.gov/pubmed/35344086 http://dx.doi.org/10.1007/s00018-022-04237-x |
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