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Prediabetes blunts DPP4 genetic control of postprandial glycaemia and insulin secretion

AIMS/HYPOTHESIS: Imbalances in glucose metabolism are hallmarks of clinically silent prediabetes (defined as impaired fasting glucose and/or impaired glucose tolerance) representing dysmetabolism trajectories leading to type 2 diabetes. CD26/dipeptidyl peptidase 4 (DPP4) is a clinically proven molec...

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Detalles Bibliográficos
Autores principales: Patarrão, Rita S., Duarte, Nádia, Coelho, Inês, Ward, Joey, Ribeiro, Rogério T., Meneses, Maria João, Andrade, Rita, Costa, João, Correia, Isabel, Boavida, José Manuel, Duarte, Rui, Gardete-Correia, Luís, Medina, José Luís, Pell, Jill, Petrie, John, Raposo, João F., Macedo, Maria Paula, Penha-Gonçalves, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960640/
https://www.ncbi.nlm.nih.gov/pubmed/35190847
http://dx.doi.org/10.1007/s00125-021-05638-6