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Identification of Epigenetically Modified Hub Genes and Altered Pathways Associated With Retinoblastoma
Retinoblastoma (Rb) is the most common childhood malignancy initiated by biallelic mutation in RB1 gene and driven by various epigenetic events including DNA methylation and microRNA dysregulation. Hence, understanding the key genes that are critically modulated by epigenetic modifications in RB1 (...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960645/ https://www.ncbi.nlm.nih.gov/pubmed/35359459 http://dx.doi.org/10.3389/fcell.2022.743224 |