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Identification of Epigenetically Modified Hub Genes and Altered Pathways Associated With Retinoblastoma

Retinoblastoma (Rb) is the most common childhood malignancy initiated by biallelic mutation in RB1 gene and driven by various epigenetic events including DNA methylation and microRNA dysregulation. Hence, understanding the key genes that are critically modulated by epigenetic modifications in RB1 (...

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Detalles Bibliográficos
Autores principales: Karmakar, Aditi, Ahamad Khan, Md. Maqsood, Kumari, Nidhi, Devarajan, Nalini, Ganesan, Senthil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960645/
https://www.ncbi.nlm.nih.gov/pubmed/35359459
http://dx.doi.org/10.3389/fcell.2022.743224