Endothelial glycocalyx is damaged in diabetic cardiomyopathy: angiopoietin 1 restores glycocalyx and improves diastolic function in mice

AIMS/HYPOTHESIS: Diabetic cardiomyopathy (DCM) is a serious and under-recognised complication of diabetes. The first sign is diastolic dysfunction, which progresses to heart failure. The pathophysiology of DCM is incompletely understood but microcirculatory changes are important. Endothelial glycoca...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Yan, Buffonge, Stanley, Ramnath, Raina, Jenner, Sophie, Fawaz, Sarah, Arkill, Kenton P., Neal, Chris, Verkade, Paul, White, Stephen J., Hezzell, Melanie, Salmon, Andrew H. J., Suleiman, M.-Saadeh, Welsh, Gavin I., Foster, Rebecca R., Madeddu, Paolo, Satchell, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960650/
https://www.ncbi.nlm.nih.gov/pubmed/35211778
http://dx.doi.org/10.1007/s00125-022-05650-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960650/
https://www.ncbi.nlm.nih.gov/pubmed/35211778
http://dx.doi.org/10.1007/s00125-022-05650-4

Ejemplares similares