Structural basis of R-loop recognition by the S9.6 monoclonal antibody

R-loops are ubiquitous, dynamic nucleic-acid structures that play fundamental roles in DNA replication and repair, chromatin and transcription regulation, as well as telomere maintenance. The DNA-RNA hybrid–specific S9.6 monoclonal antibody is widely used to map R-loops. Here, we report crystal stru...

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Detalles Bibliográficos
Autores principales: Bou-Nader, Charles, Bothra, Ankur, Garboczi, David N., Leppla, Stephen H., Zhang, Jinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960830/
https://www.ncbi.nlm.nih.gov/pubmed/35347133
http://dx.doi.org/10.1038/s41467-022-29187-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960830/
https://www.ncbi.nlm.nih.gov/pubmed/35347133
http://dx.doi.org/10.1038/s41467-022-29187-7

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