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Coating Ti6Al4V implants with nanocrystalline diamond functionalized with BMP-7 promotes extracellular matrix mineralization in vitro and faster osseointegration in vivo

The present study investigates the effect of an oxidized nanocrystalline diamond (O-NCD) coating functionalized with bone morphogenetic protein 7 (BMP-7) on human osteoblast maturation and extracellular matrix mineralization in vitro and on new bone formation in vivo. The chemical structure and the...

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Detalles Bibliográficos
Autores principales: Nemcakova, Ivana, Litvinec, Andrej, Mandys, Vaclav, Potocky, Stepan, Plencner, Martin, Doubkova, Martina, Nanka, Ondrej, Olejnickova, Veronika, Sankova, Barbora, Bartos, Martin, Ukraintsev, Egor, Babčenko, Oleg, Bacakova, Lucie, Kromka, Alexander, Rezek, Bohuslav, Sedmera, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960880/
https://www.ncbi.nlm.nih.gov/pubmed/35347219
http://dx.doi.org/10.1038/s41598-022-09183-z