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Lipidomic Analysis of TRPC1 Ca(2+)-Permeable Channel-Knock Out Mouse Demonstrates a Vital Role in Placental Tissue Sphingolipid and Triacylglycerol Homeostasis Under Maternal High-Fat Diet

The transient receptor potential canonical channel 1 (TRPC1) is a ubiquitous Ca(2+)-permeable integral membrane protein present in most tissues, including adipose and placenta, and functionally regulates energetic homeostasis. We demonstrated that elimination of TRPC1 in a mouse model increased body...

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Detalles Bibliográficos
Autores principales: Bukowski, Michael R., Singh, Brij B., Roemmich, James N., Claycombe-Larson, Kate J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960927/
https://www.ncbi.nlm.nih.gov/pubmed/35360063
http://dx.doi.org/10.3389/fendo.2022.854269