Fbw7 Inhibits the Progression of Activated B-Cell Like Diffuse Large B-Cell Lymphoma by Targeting the Positive Feedback Loop of the LDHA/lactate/miR-223 Axis

BACKGROUND: F-box and WD repeat domain-containing 7 (Fbw7) is well known as a tumor suppressor and ubiquitin ligase which targets a variety of oncogenic proteins for proteolysis. We previously reported that Fbw7 promotes apoptosis in diffuse large B-cell lymphoma (DLBCL) through Fbw7-mediated ubiqui...

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Detalles Bibliográficos
Autores principales: Yao, Su, Guo, Tairan, Zhang, Fen, Chen, Yu, Xu, Fangping, Luo, Donglan, Luo, Xinlan, Lin, Danyi, Chen, Wendan, Li, Zhi, Liu, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960958/
https://www.ncbi.nlm.nih.gov/pubmed/35359405
http://dx.doi.org/10.3389/fonc.2022.842356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960958/
https://www.ncbi.nlm.nih.gov/pubmed/35359405
http://dx.doi.org/10.3389/fonc.2022.842356

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