DNA methylation profiles differ in responders versus non-responders to anti-PD-1 immune checkpoint inhibitors in patients with advanced and metastatic head and neck squamous cell carcinoma

BACKGROUND: Biomarkers for response prediction to anti-programmed cell death 1 (PD-1) immune checkpoint inhibitors (ICI) in patients with head and neck squamous cell carcinoma (HNSCC) are urgently needed for a personalized therapy approach. We investigated the predictive potential of inflammatory pa...

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Detalles Bibliográficos
Autores principales: Starzer, Angelika Martina, Heller, Gerwin, Tomasich, Erwin, Melchardt, Thomas, Feldmann, Katharina, Hatziioannou, Teresa, Traint, Stefan, Minichsdorfer, Christoph, Schwarz-Nemec, Ursula, Nackenhorst, Maja, Müllauer, Leonhard, Preusser, Matthias, Berghoff, Anna Sophie, Fuereder, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961155/
https://www.ncbi.nlm.nih.gov/pubmed/35338086
http://dx.doi.org/10.1136/jitc-2021-003420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961155/
https://www.ncbi.nlm.nih.gov/pubmed/35338086
http://dx.doi.org/10.1136/jitc-2021-003420

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