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Real-Time Search-Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

In the young field of single-cell proteomics (scMS), there is a great need for improved global proteome characterization, both in terms of proteins quantified per cell and quantitative performance thereof. The recently introduced real-time search (RTS) on the Orbitrap Eclipse Tribrid mass spectromet...

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Detalles Bibliográficos
Autores principales: Furtwängler, Benjamin, Üresin, Nil, Motamedchaboki, Khatereh, Huguet, Romain, Lopez-Ferrer, Daniel, Zabrouskov, Vlad, Porse, Bo T., Schoof, Erwin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961214/
https://www.ncbi.nlm.nih.gov/pubmed/35219906
http://dx.doi.org/10.1016/j.mcpro.2022.100219