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IP3R1/GRP75/VDAC1 complex mediates endoplasmic reticulum stress-mitochondrial oxidative stress in diabetic atrial remodeling

RATIONALE: Endoplasmic reticulum (ER) stress and mitochondrial dysfunction are important mechanisms of atrial remodeling, predisposing to the development of atrial fibrillation (AF) in type 2 diabetes mellitus (T2DM). However, the molecular mechanisms underlying these processes especially their inte...

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Detalles Bibliográficos
Autores principales: Yuan, Ming, Gong, Mengqi, He, Jinli, Xie, Bingxin, Zhang, Zhiwei, Meng, Lei, Tse, Gary, Zhao, Yungang, Bao, Qiankun, Zhang, Yue, Yuan, Meng, Liu, Xing, Luo, Cunjin, Wang, Feng, Li, Guangping, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961221/
https://www.ncbi.nlm.nih.gov/pubmed/35344886
http://dx.doi.org/10.1016/j.redox.2022.102289