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Non-canonical ubiquitylation makes its mark on Rap2 and cell motility

Ubiquitin modification controls protein stability and cargo trafficking, and in this issue Duncan et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202107114) reveal a unique mechanism through which Rab40b/Cul5-mediated ubiquitylation of Rap2 regulates its activity and recycling to the leading...

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Detalles Bibliográficos
Autor principal: Caswell, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961291/
https://www.ncbi.nlm.nih.gov/pubmed/35333280
http://dx.doi.org/10.1083/jcb.202203029