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Molecularly engineered tumor acidity-responsive plant toxin gelonin for safe and efficient cancer therapy

Due to the unsatisfactory therapeutic efficacy and inexorable side effects of small molecule antineoplastic agents, extensive efforts have been devoted to the development of more potent macromolecular agents with high specificity. Gelonin is a plant-derived protein toxin that exhibits robust antitum...

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Detalles Bibliográficos
Autores principales: Ding, Guo-Bin, Zhu, Chenchen, Wang, Qian, Cao, Huiyan, Li, Bin-Chun, Yang, Peng, Stauber, Roland H., Nie, Guangjun, Li, Zhuoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961304/
https://www.ncbi.nlm.nih.gov/pubmed/35387163
http://dx.doi.org/10.1016/j.bioactmat.2022.02.001