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Molecularly engineered tumor acidity-responsive plant toxin gelonin for safe and efficient cancer therapy
Due to the unsatisfactory therapeutic efficacy and inexorable side effects of small molecule antineoplastic agents, extensive efforts have been devoted to the development of more potent macromolecular agents with high specificity. Gelonin is a plant-derived protein toxin that exhibits robust antitum...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961304/ https://www.ncbi.nlm.nih.gov/pubmed/35387163 http://dx.doi.org/10.1016/j.bioactmat.2022.02.001 |