Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease

Synapse loss is associated with cognitive decline in Alzheimer’s disease, and owing to their plastic nature, synapses are an ideal target for therapeutic intervention. Oligomeric amyloid beta around amyloid plaques is known to contribute to synapse loss in mouse models and is associated with synapse...

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Detalles Bibliográficos
Autores principales: Yeap, Jie, Sathyaprakash, Chaitra, Toombs, Jamie, Tulloch, Jane, Scutariu, Cristina, Rose, Jamie, Burr, Karen, Davies, Caitlin, Colom-Cadena, Marti, Chandran, Siddharthan, Large, Charles H., Rowan, Matthew J. M., Gunthorpe, Martin J., Spires-Jones, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961358/
https://www.ncbi.nlm.nih.gov/pubmed/35359460
http://dx.doi.org/10.1177/23982128221086464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961358/
https://www.ncbi.nlm.nih.gov/pubmed/35359460
http://dx.doi.org/10.1177/23982128221086464

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