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Potential Effects of Boldine on Oxidative Stress, Apoptosis, and Inflammatory Changes Induced by the Methylprednisolone Hepatotoxicity in Male Wistar Rats

BACKGROUND: Synthetic glucocorticoid therapeutic agent methylprednisolone (MPL), when used for an extended period of time at high dose, promotes the development of reactive oxygen species (ROS)-induced liver toxicity. This study investigated the role of boldine, a natural antioxidant with anti-apopt...

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Detalles Bibliográficos
Autores principales: Shuker, Esraa, Farhood, Manal, Al-Qudaihi, Ghofran, Fouad, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961387/
https://www.ncbi.nlm.nih.gov/pubmed/35360456
http://dx.doi.org/10.1177/15593258221082877