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Mobile origin-licensing factors confer resistance to conflicts with RNA polymerase

Fundamental to our understanding of chromosome duplication is the idea that replication origins function both as sites where MCM helicases are loaded during the G1 phase and where synthesis begins in S phase. However, the temporal delay between phases exposes the replisome assembly pathway to potent...

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Detalles Bibliográficos
Autores principales: Scherr, Matthias J., Wahab, Syafiq Abd, Remus, Dirk, Duderstadt, Karl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961423/
https://www.ncbi.nlm.nih.gov/pubmed/35320708
http://dx.doi.org/10.1016/j.celrep.2022.110531