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The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN), the most common microvascular complication in patients with diabetes, induces kidney failure. Previous research showed that endothelial-to-mesenchymal transition (EndMT) of human glomerular endothelial cells (HGECs) is involved in the progression of DN. Moreove...

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Detalles Bibliográficos
Autores principales: Li, Xue, Lu, Lihong, Hou, Wenting, Wang, Fei, Huang, Ting, Meng, Zhipeng, Zhu, Minmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961497/
https://www.ncbi.nlm.nih.gov/pubmed/35351142
http://dx.doi.org/10.1186/s12967-022-03352-4