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Biologically Relevant In Vitro 3D-Model to Study Bone Regeneration Potential of Human Adipose Stem Cells

Standard cell cultures may not predict the proliferation and differentiation potential of human mesenchymal stromal cells (MSCs) after seeding on a scaffold and implanting this construct in a bone defect. We aimed to develop a more biologically relevant in vitro 3D-model for preclinical studies on t...

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Detalles Bibliográficos
Autores principales: van Santen, Victor J. B., Bastidas Coral, Angela P., Hogervorst, Jolanda M. A., Klein-Nulend, Jenneke, Bakker, Astrid D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961519/
https://www.ncbi.nlm.nih.gov/pubmed/35204670
http://dx.doi.org/10.3390/biom12020169