Retinoic Acid Grafted to Hyaluronic Acid Activates Retinoid Gene Expression and Removes Cholesterol from Cellular Membranes

All-trans-retinoic acid (atRA) is a potent ligand that regulates gene expression and is used to treat several skin disorders. Hyaluronic acid (HA) was previously conjugated with atRA (HA-atRA) to obtain a novel amphiphilic compound. HA-atRA forms micelles that incorporate hydrophobic molecules and f...

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Detalles Bibliográficos
Autores principales: Pavlík, Vojtěch, Machalová, Veronika, Čepa, Martin, Šínová, Romana, Šafránková, Barbora, Kulhánek, Jaromír, Drmota, Tomáš, Kubala, Lukáš, Huerta-Ángeles, Gloria, Velebný, Vladimír, Nešporová, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961547/
https://www.ncbi.nlm.nih.gov/pubmed/35204701
http://dx.doi.org/10.3390/biom12020200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961547/
https://www.ncbi.nlm.nih.gov/pubmed/35204701
http://dx.doi.org/10.3390/biom12020200

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