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DOTA: Deep Learning Optimal Transport Approach to Advance Drug Repositioning for Alzheimer’s Disease

Alzheimer’s disease (AD) is the leading cause of age-related dementia, affecting over 5 million people in the United States and incurring a substantial global healthcare cost. Unfortunately, current treatments are only palliative and do not cure AD. There is an urgent need to develop novel anti-AD t...

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Detalles Bibliográficos
Autores principales: Chyr, Jacqueline, Gong, Haoran, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961573/
https://www.ncbi.nlm.nih.gov/pubmed/35204697
http://dx.doi.org/10.3390/biom12020196