Targeted NMDA Receptor Interventions for Autism: Developmentally Determined Expression of GluN2B and GluN2A-Containing Receptors and Balanced Allosteric Modulatory Approaches

Various ASD risk alleles have been associated with impairment of NMDA receptor activation (i.e., NMDA Receptor Hypofunction) and/or disturbance of the careful balance between activation mediated by GluN2B-subtype and GluN2A-subtype-containing NMDA receptors. Importantly, although these various risk...

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Detalles Bibliográficos
Autores principales: Deutsch, Stephen I., Luyo, Zachary N. M., Burket, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961601/
https://www.ncbi.nlm.nih.gov/pubmed/35204682
http://dx.doi.org/10.3390/biom12020181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961601/
https://www.ncbi.nlm.nih.gov/pubmed/35204682
http://dx.doi.org/10.3390/biom12020181

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