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Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A and Withanone

Withaferin-A (Wi-A), a secondary metabolite extracted from Ashwagandha (Withania somnifera), has been shown to possess anticancer activity. However, the molecular mechanism of its action and the signaling pathways have not yet been fully explored. We performed an inverse virtual screening to investi...

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Detalles Bibliográficos
Autores principales: Malik, Vidhi, Radhakrishnan, Navaneethan, Kaul, Sunil C., Wadhwa, Renu, Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961606/
https://www.ncbi.nlm.nih.gov/pubmed/35204712
http://dx.doi.org/10.3390/biom12020212