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E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans
Notch is a developmental receptor, conserved in the evolution of the metazoa, which regulates cell fate proliferation and survival in numerous developmental contexts, and also regulates tissue renewal and repair in adult organisms. Notch is activated by proteolytic removal of its extracellular domai...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961608/ https://www.ncbi.nlm.nih.gov/pubmed/35204725 http://dx.doi.org/10.3390/biom12020224 |