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E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans

Notch is a developmental receptor, conserved in the evolution of the metazoa, which regulates cell fate proliferation and survival in numerous developmental contexts, and also regulates tissue renewal and repair in adult organisms. Notch is activated by proteolytic removal of its extracellular domai...

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Detalles Bibliográficos
Autores principales: Revici, Raluca, Hosseini-Alghaderi, Samira, Haslam, Fabienne, Whiteford, Rory, Baron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961608/
https://www.ncbi.nlm.nih.gov/pubmed/35204725
http://dx.doi.org/10.3390/biom12020224