Differences in Medium-Induced Conformational Plasticity Presumably Underlie Different Cytotoxic Activity of Ricin and Viscumin

Structurally similar catalytic subunits A of ricin (RTA) and viscumin (MLA) exhibit cytotoxic activity through ribosome inactivation. Ricin is more cytotoxic than viscumin, although the molecular mechanisms behind this difference are still poorly understood. To shed more light on this problem, we us...

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Detalles Bibliográficos
Autores principales: Volynsky, Pavel, Maltseva, Diana, Tabakmakher, Valentin, Bocharov, Eduard V., Raygorodskaya, Maria, Zakharova, Galina, Britikova, Elena, Tonevitsky, Alexander, Efremov, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961613/
https://www.ncbi.nlm.nih.gov/pubmed/35204796
http://dx.doi.org/10.3390/biom12020295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961613/
https://www.ncbi.nlm.nih.gov/pubmed/35204796
http://dx.doi.org/10.3390/biom12020295

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