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Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration

Defensins form an integral part of the cationic host defence peptide (HDP) family, a key component of innate immunity. Apart from their antimicrobial and immunomodulatory activities, many HDPs exert multifaceted effects on tumour cells, notably direct oncolysis and/or inhibition of tumour cell migra...

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Detalles Bibliográficos
Autores principales: Bindra, Guneet K., Williams, Scott A., Lay, Fung T., Baxter, Amy A., Poon, Ivan K. H., Hulett, Mark D., Phan, Thanh Kha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961614/
https://www.ncbi.nlm.nih.gov/pubmed/35204765
http://dx.doi.org/10.3390/biom12020264