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CNS-Sparing Histamine H(3) Receptor Antagonist as a Candidate to Prevent the Diabetes-Associated Gastrointestinal Symptoms

Among the histamine receptors, growing evidence points to the histamine H(3) receptor as a pharmacological candidate to counteract the autonomic neuropathy associated with diabetes. The study aimed to evaluate the effect of PF00868087 (also known as ZPL-868), a CNS-sparing histamine H(3) receptor an...

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Detalles Bibliográficos
Autores principales: Rosa, Arianna Carolina, Nardini, Patrizia, Sgambellone, Silvia, Gurrieri, Maura, Spampinato, Simona Federica, Dell’Accio, Alfonso, Chazot, Paul L, Obara, Ilona, Liu, Wai L, Pini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961615/
https://www.ncbi.nlm.nih.gov/pubmed/35204685
http://dx.doi.org/10.3390/biom12020184