PrimPol: A Breakthrough among DNA Replication Enzymes and a Potential New Target for Cancer Therapy

DNA replication can encounter blocking obstacles, leading to replication stress and genome instability. There are several mechanisms for evading this blockade. One mechanism consists of repriming ahead of the obstacles, creating a new starting point; in humans, PrimPol is responsible for carrying ou...

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Detalles Bibliográficos
Autores principales: Díaz-Talavera, Alberto, Montero-Conde, Cristina, Leandro-García, Luis Javier, Robledo, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961649/
https://www.ncbi.nlm.nih.gov/pubmed/35204749
http://dx.doi.org/10.3390/biom12020248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961649/
https://www.ncbi.nlm.nih.gov/pubmed/35204749
http://dx.doi.org/10.3390/biom12020248

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