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Trpm8 Expression in Human and Mouse Castration Resistant Prostate Adenocarcinoma Paves the Way for the Preclinical Development of TRPM8-Based Targeted Therapies

Metastatic prostate cancer (mPCa) is one of the leading causes of cancer-related mortality in both the US and Europe. Androgen deprivation is the first-line therapy for mPCa; however, resistance to therapy inevitably occurs and the disease progresses to the castration resistant stage, which is uncur...

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Detalles Bibliográficos
Autores principales: Genovesi, Sacha, Moro, Riccardo, Vignoli, Beatrice, De Felice, Dario, Canossa, Marco, Montironi, Rodolfo, Carbone, Francesco Giuseppe, Barbareschi, Mattia, Lunardi, Andrea, Alaimo, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961668/
https://www.ncbi.nlm.nih.gov/pubmed/35204694
http://dx.doi.org/10.3390/biom12020193