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Metal-Free Diastereo- and Enantioselective Dearomative Formal [3 + 2] Cycloaddition of 2-Nitrobenzofurans and Isocyanoacetate Esters

[Image: see text] The diastereo- and enantioselective dearomative formal [3 + 2] cycloaddition of 2-nitrobenzofurans and α-aryl-α-isocyanoacetate esters provides tricyclic compounds bearing the 3a,8b-dihydro-1H-benzofuro[2,3-c]pyrrole framework with three consecutive stereogenic centers. The reactio...

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Detalles Bibliográficos
Autores principales: Laviós, Adrian, Sanz-Marco, Amparo, Vila, Carlos, Muñoz, M. Carmen, Pedro, José R., Blay, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961877/
https://www.ncbi.nlm.nih.gov/pubmed/35293212
http://dx.doi.org/10.1021/acs.orglett.2c00427