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Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis

The activation and dysregulation of retrotransposons has been identified in the CNS of individuals with the fatal neurodegenerative disorder Amyotrophic lateral sclerosis (ALS). This includes elements from multiple different families and subfamilies of retrotransposons, however there is limited know...

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Detalles Bibliográficos
Autores principales: Pfaff, Abigail L., Bubb, Vivien J., Quinn, John P., Koks, Sulev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961898/
https://www.ncbi.nlm.nih.gov/pubmed/35346298
http://dx.doi.org/10.1186/s13041-022-00914-x