Repeat-dose and local tolerance toxicity of SARS-CoV-2 FINLAY-FR-02 vaccine candidate in Sprague Dawley rats

This study evaluates safety of FINLAY-FR-02, a vaccine candidate against SARS-CoV-2 based on the recombinant receptor binding domain conjugated to tetanus toxoid, in a preclinical, repeat-dose toxicity and local tolerance study. Sprague Dawley rats were randomly allocated to three experimental group...

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Detalles Bibliográficos
Autores principales: Oliva-Hernández, Reynaldo, Fariñas-Medina, Mildrey, Hernández-Salazar, Tamara, Oyarzabal-Vera, Ambar, Infante-Bourzac, Juan F., Rodríguez-Salgueiro, Sandra, Rodríguez-Noda, Laura M., Arranguren-Masorra, Yisabel, Climent-Ruíz, Yanet, Fernández-Castillo, Sonsire, G-Rivera, Daniel, Santana-Mederos, Darielys, Sánchez-Ramírez, Belinda, García-Rivera, Dagmar, Valdés-Barbín, Yury, Vérez-Bencomo, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961942/
https://www.ncbi.nlm.nih.gov/pubmed/35364223
http://dx.doi.org/10.1016/j.tox.2022.153161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961942/
https://www.ncbi.nlm.nih.gov/pubmed/35364223
http://dx.doi.org/10.1016/j.tox.2022.153161

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