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BMI1 promotes osteosarcoma proliferation and metastasis by repressing the transcription of SIK1

BACKGROUND: Osteosarcoma (OS) is the most common malignant tumor of bone, and the clinical efficacy of current treatments and associated survival rates need to be further improved by employing novel therapeutic strategies. Although various studies have shown that BMI1 protein is universally upregula...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Wu, Yinghui, Lin, Meng, Wang, Gaigai, Liu, Jinyan, Xie, Min, Zheng, Bo, Shen, Cong, Shen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961961/
https://www.ncbi.nlm.nih.gov/pubmed/35346195
http://dx.doi.org/10.1186/s12935-022-02552-8