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Corticosteroid suppresses urea-cycle-related gene expressions in ornithine transcarbamylase deficiency

BACKGROUND: Ornithine transcarbamylase deficiency (OTCD) is most common among urea cycle disorders (UCDs), defined by defects in enzymes associated with ureagenesis. Corticosteroid administration to UCD patients, including OTCD patients, is suggested to be avoided, as it may induce life-threatening...

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Detalles Bibliográficos
Autores principales: Imoto, Koji, Tanaka, Masatake, Goya, Takeshi, Aoyagi, Tomomi, Takahashi, Motoi, Kurokawa, Miho, Tashiro, Shigeki, Kato, Masaki, Kohjima, Motoyuki, Ogawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962007/
https://www.ncbi.nlm.nih.gov/pubmed/35346058
http://dx.doi.org/10.1186/s12876-022-02213-0