hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers

BACKGROUND: The tyrosine kinase receptor encoded by the MET oncogene is a major player in cancer. When MET is responsible for the onset and progression of the transformed phenotype (MET-addicted cancers), an efficient block of its oncogenic activation results in potent tumor growth inhibition. METHO...

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Detalles Bibliográficos
Autores principales: Martinelli, Ilaria, Modica, Chiara, Chiriaco, Cristina, Basilico, Cristina, Hughes, James M., Corso, Simona, Giordano, Silvia, Comoglio, Paolo M., Vigna, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962049/
https://www.ncbi.nlm.nih.gov/pubmed/35351166
http://dx.doi.org/10.1186/s13046-022-02320-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962049/
https://www.ncbi.nlm.nih.gov/pubmed/35351166
http://dx.doi.org/10.1186/s13046-022-02320-6

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