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Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice

BACKGROUND: Recent findings show that extracellular vesicle constituents can exert short- and long-range biological effects on neighboring cells in the brain, opening an exciting avenue for investigation in the field of neurodegenerative diseases. Although it is well documented that extracellular ve...

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Detalles Bibliográficos
Autores principales: Pergande, Melissa R., Kang, Christina, George, Diann, Sutter, Pearl A., Crocker, Stephen J., Cologna, Stephanie M., Givogri, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962106/
https://www.ncbi.nlm.nih.gov/pubmed/35351138
http://dx.doi.org/10.1186/s12944-022-01644-8