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Suppressive effect of α-mangostin for cancer stem cells in colorectal cancer via the Notch pathway
BACKGROUND: Since colon cancer stem cells (CSCs) play an important role in chemoresistance and in tumor recurrence and metastasis, targeting of CSCs has emerged as a sophisticated strategy for cancer therapy. α-mangostin (αM) has been confirmed to have antiproliferative and apoptotic effects on canc...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962146/ https://www.ncbi.nlm.nih.gov/pubmed/35351071 http://dx.doi.org/10.1186/s12885-022-09414-6 |