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Suppressive effect of α-mangostin for cancer stem cells in colorectal cancer via the Notch pathway

BACKGROUND: Since colon cancer stem cells (CSCs) play an important role in chemoresistance and in tumor recurrence and metastasis, targeting of CSCs has emerged as a sophisticated strategy for cancer therapy. α-mangostin (αM) has been confirmed to have antiproliferative and apoptotic effects on canc...

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Detalles Bibliográficos
Autores principales: Jo, Min Kyoung, Moon, Chang Mo, Kim, Eun Ju, Kwon, Ji-Hee, Fei, Xiang, Kim, Seong-Eun, Jung, Sung-Ae, Kim, Minsuk, Mun, Yeung-Chul, Ahn, Young-Ho, Seo, Seung-Yong, Kim, Tae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962146/
https://www.ncbi.nlm.nih.gov/pubmed/35351071
http://dx.doi.org/10.1186/s12885-022-09414-6