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Chicago sky blue 6B inhibits α-synuclein aggregation and propagation

Abnormal deposition of α-synuclein aggregates in Lewy bodies and Lewy neurites is the hallmark lesion in Parkinson’s disease (PD). These aggregates, thought to be the culprit of disease pathogenesis, spread throughout the brain as the disease progresses. Agents that inhibit α-synuclein aggregation a...

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Detalles Bibliográficos
Autores principales: Min, Joo-Ok, Strohäker, Timo, Jeong, Byung-Chul, Zweckstetter, Markus, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962151/
https://www.ncbi.nlm.nih.gov/pubmed/35346306
http://dx.doi.org/10.1186/s13041-022-00913-y