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Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro

BACKGROUND: Microglia, the resident immune cells of the brain, play a critical role in numerous diseases, but are a minority cell type and difficult to genetically manipulate in vivo with viral vectors and other approaches. Primary cultures allow a more controlled setting to investigate these cells,...

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Detalles Bibliográficos
Autores principales: Cadiz, Mika P., Jensen, Tanner D., Sens, Jonathon P., Zhu, Kuixi, Song, Won-Min, Zhang, Bin, Ebbert, Mark, Chang, Rui, Fryer, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962153/
https://www.ncbi.nlm.nih.gov/pubmed/35346293
http://dx.doi.org/10.1186/s13024-022-00531-1