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Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro
BACKGROUND: Microglia, the resident immune cells of the brain, play a critical role in numerous diseases, but are a minority cell type and difficult to genetically manipulate in vivo with viral vectors and other approaches. Primary cultures allow a more controlled setting to investigate these cells,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962153/ https://www.ncbi.nlm.nih.gov/pubmed/35346293 http://dx.doi.org/10.1186/s13024-022-00531-1 |