Cargando…
Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro
BACKGROUND: Microglia, the resident immune cells of the brain, play a critical role in numerous diseases, but are a minority cell type and difficult to genetically manipulate in vivo with viral vectors and other approaches. Primary cultures allow a more controlled setting to investigate these cells,...
Autores principales: | Cadiz, Mika P., Jensen, Tanner D., Sens, Jonathon P., Zhu, Kuixi, Song, Won-Min, Zhang, Bin, Ebbert, Mark, Chang, Rui, Fryer, John D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962153/ https://www.ncbi.nlm.nih.gov/pubmed/35346293 http://dx.doi.org/10.1186/s13024-022-00531-1 |
Ejemplares similares
-
Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau
por: Kang, Silvia S., et al.
Publicado: (2018) -
Microglial heterogeneity after subarachnoid haemorrhage
por: Galea, Ian
Publicado: (2022) -
Hyperglycaemia and apoptosis of microglial cells in human septic shock
por: Polito, Andrea, et al.
Publicado: (2011) -
Microglial regional heterogeneity and its role in the brain
por: Tan, Yun-Long, et al.
Publicado: (2019) -
Exploring genes that control microglial heterogeneity and transition
por: Okajima, Tomomi, et al.
Publicado: (2021)