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The zinc transporter ZIP12 regulates monocrotaline-induced proliferation and migration of pulmonary arterial smooth muscle cells via the AKT/ERK signaling pathways

BACKGROUND: The zinc transporter ZIP12 is a membrane-spanning protein that transports zinc ions into the cytoplasm from the extracellular space. Recent studies demonstrated that upregulation of ZIP12 is involved in elevation of cytosolic free zinc and excessive proliferation of pulmonary arterial sm...

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Detalles Bibliográficos
Autores principales: Ye, Chaoyi, Lian, Guili, Wang, Tingjun, Chen, Ai, Chen, Weixiao, Gong, Jin, Luo, Li, Wang, Huajun, Xie, Liangdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962172/
https://www.ncbi.nlm.nih.gov/pubmed/35346134
http://dx.doi.org/10.1186/s12890-022-01905-3