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The zinc transporter ZIP12 regulates monocrotaline-induced proliferation and migration of pulmonary arterial smooth muscle cells via the AKT/ERK signaling pathways
BACKGROUND: The zinc transporter ZIP12 is a membrane-spanning protein that transports zinc ions into the cytoplasm from the extracellular space. Recent studies demonstrated that upregulation of ZIP12 is involved in elevation of cytosolic free zinc and excessive proliferation of pulmonary arterial sm...
Autores principales: | Ye, Chaoyi, Lian, Guili, Wang, Tingjun, Chen, Ai, Chen, Weixiao, Gong, Jin, Luo, Li, Wang, Huajun, Xie, Liangdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962172/ https://www.ncbi.nlm.nih.gov/pubmed/35346134 http://dx.doi.org/10.1186/s12890-022-01905-3 |
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