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Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer

The development of multidrug resistance (MDR) during cancer chemotherapy is a major challenge in current cancer treatment strategies. Numerous molecular mechanisms, including increased drug efflux, evasion of drug-induced apoptosis, and activation of DNA repair mechanisms, can drive chemotherapy res...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangyang, Wang, Min, Feng, Junyi, Qin, Bin, Zhang, Chenglin, Zhu, Chengshen, Liu, Wentao, Wang, Yaohe, Liu, Wei, Huang, Lei, Lu, Shuangshuang, Wang, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962182/
https://www.ncbi.nlm.nih.gov/pubmed/35346194
http://dx.doi.org/10.1186/s12951-022-01377-x