Cargando…
Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer
The development of multidrug resistance (MDR) during cancer chemotherapy is a major challenge in current cancer treatment strategies. Numerous molecular mechanisms, including increased drug efflux, evasion of drug-induced apoptosis, and activation of DNA repair mechanisms, can drive chemotherapy res...
Autores principales: | Zhang, Xiangyang, Wang, Min, Feng, Junyi, Qin, Bin, Zhang, Chenglin, Zhu, Chengshen, Liu, Wentao, Wang, Yaohe, Liu, Wei, Huang, Lei, Lu, Shuangshuang, Wang, Zhimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962182/ https://www.ncbi.nlm.nih.gov/pubmed/35346194 http://dx.doi.org/10.1186/s12951-022-01377-x |
Ejemplares similares
-
Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment
por: Zhang, Xiangyang, et al.
Publicado: (2022) -
Inhibition of MDR1 expression with altritol-modified siRNAs
por: Fisher, Michael, et al.
Publicado: (2007) -
Enhanced therapeutic effect of Adriamycin on multidrug resistant breast cancer by the ABCG2-siRNA loaded polymeric nanoparticles assisted with ultrasound
por: Bai, Min, et al.
Publicado: (2015) -
Rational design of microRNA–siRNA chimeras for multifunctional target suppression
por: Jiang, Zhou, et al.
Publicado: (2013) -
Cetuximab-Modified Human Serum Albumin Nanoparticles Co-Loaded with Doxorubicin and MDR1 siRNA for the Treatment of Drug-Resistant Breast Tumors
por: Yang, Xin, et al.
Publicado: (2021)