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New Tricks with Old Dogs: Computational Identification and Experimental Validation of New miRNA–mRNA Regulation in hiPSC-CMs

Cardiovascular disease is still the leading cause of morbidity and mortality worldwide. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have become a valuable widespread in vitro model to study cardiac disease. Herein, we employ the hiPSC-CM model to identify novel miRNA–mRNA...

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Detalles Bibliográficos
Autores principales: Bencun, Maja, Britto-Borges, Thiago, Eschenbach, Jessica, Dieterich, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962266/
https://www.ncbi.nlm.nih.gov/pubmed/35203600
http://dx.doi.org/10.3390/biomedicines10020391