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Activation of Calcium-Activated Chloride Channels Suppresses Inherited Seizure Susceptibility in Genetically Epilepsy-Prone Rats

Inherited seizure susceptibility in genetically epilepsy-prone rats (GEPR-3s) is associated with increased voltage-gated calcium channel currents suggesting a massive calcium influx resulting in increased levels of intraneuronal calcium. Cytosolic calcium, in turn, activates many processes, includin...

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Detalles Bibliográficos
Autores principales: Thomas, Miracle, Simms, Mark, N’Gouemo, Prosper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962295/
https://www.ncbi.nlm.nih.gov/pubmed/35203658
http://dx.doi.org/10.3390/biomedicines10020449