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A Rationale for the Activity of Bone Target Therapy and Tyrosine Kinase Inhibitor Combination in Giant Cell Tumor of Bone and Desmoplastic Fibroma: Translational Evidences

Giant cell tumor of bone (GCTB) and desmoplastic fibroma (DF) are bone sarcomas with intermediate malignant behavior and unpredictable prognosis. These locally aggressive neoplasms exhibit a predilection for the long bone or mandible of young adults, causing a severe bone resorption. In particular,...

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Detalles Bibliográficos
Autores principales: De Vita, Alessandro, Vanni, Silvia, Miserocchi, Giacomo, Fausti, Valentina, Pieri, Federica, Spadazzi, Chiara, Cocchi, Claudia, Liverani, Chiara, Calabrese, Chiara, Casadei, Roberto, Recine, Federica, Gurrieri, Lorena, Bongiovanni, Alberto, Ibrahim, Toni, Mercatali, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962296/
https://www.ncbi.nlm.nih.gov/pubmed/35203581
http://dx.doi.org/10.3390/biomedicines10020372